BASF
21-Nov-2019 09:19

Today is #WorldToiletDay . On this day last year, our India team inaugurated a public toilet for the local community at Bala Gram Panchayat in Mangalore. We also offer Lutropur® MSA range of organic biodegradable acids as sustainable ingredients for toilet cleaners.

#WeCreateChemistry

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Chemarc
19-Aug-2019 11:02

#HPCI is firmly rooted in India since 2010 and is recognized as the leading show for the Home and Personal Care Ingredients segment in #India . Chemarc.com was present at the #exhibition to engage with manufacturers, suppliers, and customers from all over the world, exchanging knowledge and experiences. Here are a few glimpses from the event.

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Basic Pharma Life science pvt ltd
23-Feb-2019 06:58

How to choose active pharmaceutical ingredients (API / Bulk Drug) supplier As APIs make an important component of modern medicine, supplying and acquiring constitute two important parts of it. Pharmaceutical companies therefore need to be careful in selecting right API manufacturing partners and suppliers. This article is dedicated to discuss the few aspects of a good API supplier. Chlorhexidine base Manufacturer Know your supplier: As a rule of thumb knowing the background of your supplier is a prerequisite to get assured quality products. A background search of the supplier will help you discover the many facts about his business practices, financial strengths/weaknesses, market reputation, client base, existing clients, licensing and many more. Learn about their clients: Finding out who their clients are will reveal a lot about their business. A supplier catering to the leading brands obviously is a one of repute. Most companies nowadays are candid about their client base and often showcase client feedback on their websites. While discussing about future business relations do not hesitate to ask for a few references and checking up with them before signing on those dotted lines. It is important because reputation of your business is related to that. Guarantee about products: Is your supplier ready to vouch for the ingredients supplied by them? Are they ready to take responsibility about product quality? Decide about the terms and conditions regarding quality assurance and assuming responsibility if a certain ingredient fail to meet quality standard. It is after all a matter of life and death for patients. Discuss the financial: Financials are one of the most important determining factors while selecting a supplier, especially, if you are looking for a long term business relation. However, costs shouldn’t remain the only selection criteria. Researching the market will help you find a supplier/manufacturer of API offering quality at reasonable cost. Get quotes for a few suppliers and then decide. Order and supply: While ordering you would also need to keep in mind if they are timely with supply. You would need to take into account shipping and other fees, such as – custom, excise, sales and other taxes and insurance costs. All these would feature into your cost of production. While deciding about supplier cost you may all these aspects into consideration. Quality: Apart from cost the other important factor that would influence your decision is quality. Aside from being competitive the supplier must also assure quality of his supply. Check out if the manufacturer had any investigations or lawsuits filed against them and if so what the verdicts of those were. Finding out also about its licensing status quo and registration details will help in decision making. API / Bulk drug manufacturer in India like Cadila Pharmaceuticals Limited can be ideal partners to deal with as they have almost all accreditations required for drug exports like USFDA, EDQM – European Directorate of Quality Medicine, Agenzia Italiana del Farmaco (AIFA), TGA – Therapeutic Goods Administration, Australia, WHO and others. Spread over more than 1,05,000 sq. ft. area, Cadila Pharmaceuticals’ R & D facilities, recognized by the Department of Science & Technology, Government of India, are manned by more than 300 scientists. A centralized Quality Control & Analytical Research Laboratory has been set up to meet the domestic and international quality standards. Basic Pharma Lifescience Pvt. Ltd. is the leading Chlorhexidine ManufacturerChlorhexidine is used along with regular tooth brushing/flossing to treat gingivitis, a gum disease. Chlorhexidine belongs to a class of drugs known as antimicrobials. It works by decreasing the amount of bacteria in the mouth, helping to reduce swelling that causes redness of the gums and bleeding when you brush. Basic Pharma Lifescience is leading manufacturer of Chlorhexidine and Cetrimide in India. The marketing team attended CPHI India Delhi 2019 to meet the multinational client for international business development. active pharmaceutical ingredient manufacturers | pharmaceutical manufacturing company india | Cetrimide Manufacturer | chlorhexidine gluconate manufacturer | Cetrimide Chemicals Manufacturer | API Intermediate manufacturers | Chlorhexidine- CAS No 55-56-1 | Cetrimide- CAS No 1119-97-7 | fine chemicals| Cetrimide intermediates | Chlorhexidine intermediates Manufacturer http://www.basicpharma.in/product/1

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KWALITY PROCESS EQUIPMENTS PVT LTD
25-Oct-2019 08:01

GENERAL PROCESS CONSIDERATIONS IN THE SELECTION OF AGITATORS FOR SIMPLE APPLICATIONS AND IMPELLER DESIGN

Classification towards Purpose

a. Blending of miscible liquids

Easiest of agitating applications and normally axial turbine or hydrofoil impellers are preferred. Jet mixing by recirculation with an ordinary pump is equally good at lower cost

b. Dissolving

In dissolving, we want provision of high flow rate and low shear past the solid surface. Unless the solid is polymeric or sticky or viscous in nature, it is an easy operation. Data solicited are solid percentage, physical characteristics with interim changes, temp, solubility and permissible dissolving time.

c. Dispersion (liquid- liquid, solid-liquid)


Dispersion refers to mixing of non-miscible liquids or of solids in liquids, into somewhat homogeneous mass whose stability is measured by its life before reasonable separation occurs. Power input varies greatly depending on purpose and impellers generally used are pitched blade turbine, or saw tooth cutter. This is most critical of mixing problems and unless properly understood, the design is liable to fail.


d. Heat exchange

Used to speed up heat transfer by forced convection. Apparently simple but for critical applications, following data helps.

Tank dimensions and details of jacket and coils, preferably G.A.drawing.

Heat transfer co-efficients

Specific heats and thermal conductivities

Temp. of batch at start and end of cycle

Temp. – Viscosity curve of components

Whether solid suspension is included

e. Emulsification

Imparting a high power to break the molecular chains and to form the oil-water emulsion with a non-ionic surfactant. Other applications are mainly in paints & lubricants sector. Some emulsion may be steady for years and some break within minutes. Static mixers are preferred than agitators for high instantaneous power resulting better emulsion but washing pump & pipeline is problematic.


f. Solids suspension

It is simple physical (like mixing) operation but power consumption varies greatly on purpose e.g. a> complete motion of solids, b> complete suspension of solids, c> complete uniformity. Power req. is in ratio of 1: 2: 5 for said operations.


g. Chemical reaction

It can be considered as combination of blending, dissolving, heat transfer, extraction, gas dispersion, and solid suspension etc. Usually an easy task from agitator designer’s point but to be sure, pilot plant study is always recommended. A haphazard selection is vulnerable and over design (like peripheral impeller tip speed) has various detrimental effects on the final product.


h. Extraction including washing and leaching

This is normally a continuous counter- current (fluidized bed) process like solid suspension involving water to be well mixed up with other ingredients and the ingredients separates out by gravity separation. Usually of interest for mining people.


i. Gas dispersion, absorption, and stripping

Gas is impregnated from bottom as small bubbles and intimately distributed throughout the liquid usually resulting a chemical reaction. Generally curved vane impeller or multiple turbines are preferred with high speed. Fully baffled tanks should be tall and narrow in construction. Pressurized chamber accelerates the process. A better way is by static mixer employing a liquid pump and a pressurized semi- permeable solid wall to impregnate gas under pressure.


j. Crystallization

It is opposite of dissolving and is accomplished by cooling a saturated solution or by heating to drive out the solvent. The heat transfer requires a good flow. Satisfactory handling of crystals is of prime importance. Pilot plant data are desired. Generally crystals deposit at the bottom but if process deserves to be uniformly suspended, much study on the crystal structure & sensitivity is to be made for speed selection. Fluid-foil or aerofoil impellers with high flow and low shear are suggested.

NOW LET US TRY TO UNDERSTAND BASIC IMPELLER DESIGN.


As like fan (for air handling) or hydel power turbines, much research has been conducted towards agitator impeller design and it is a very wide subject with much more further scope to research and improve. Impeller is designed mainly keeping in mind the purpose or application and sometimes custom built.

The basic designs are as follows.


A. Marine Propeller

Looks like a table fan blade. Suitable for high flow and low shear e.g. blending, dissolving, heat transfer, etc. Unsuitable for solid suspension, dispersion, extraction, gas dispersion, etc. flow efficiency- 50-60%. Getting outdated but manufacturers with their old proven designs are still sticking to that.

B. Pitched Blade Turbine

Looks like a table fan blade. Suitable for high flow and low shear e.g. blending, dissolving, heat transfer, etc. Unsuitable for solid suspension, dispersion, extraction, gas dispersion, etc. flow efficiency- 50-60%. Getting outdated but manufacturers with their old proven designs are still sticking to that.


C. Hydrofoil

Hydrofoil is supposed to be a foil in water and looks like pitched blade turbine with an angled cut on the lower periphery. Its flow efficiency is better than marine propeller, replacing the later in most applications and is most desired for mixing purposes but unsuitable for high shear application.

D. Aerofoil

aerofoil is having a classic stand fan blade type look and its properties are almost like hydrofoil impellers. Of interest for mining people for mineral washing and beneficiation for energy efficiency.

E. Curved Vane

Curved Vane impeller looks like straight Pelton wheel designed to hold moving particles for some time e.g. for air absorption.

F. Stator Rotor

Old outdated design supposed to bring highest shearing action and usually specified for oil-water emulsion.


G. Saw Tooth Cutter

Saw Tooth Cutter is reasonably good for handling medium to high viscous liquids. It is most economic for emulsification. Bad design for blending simple solutions as well as handling semi solids (grease, honey etc.). Suggested for oil-water emulsion, lubricants, paints, etc.

H. Anchor

Anchor (with its namely look) is used for heat transfer from bottom or scraping viscous liquids.

I. Helical Ribbon

Helical Ribbon looking like screwed ladder or double helix model of our gene. With its diameter close to tank diameter, is used for viscosity above 80 poise.

Another very effective design for handling viscous fluid is to use pitched blade turbine placed at bottom of draft tube (equaling 70% of tank dia.) at medium speed.

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